Disability
Handicap, Obstacle
noun, verbal noun
There is damage that hinders you from doing things normally. This is a disability.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.
障害があることがバレて、内定が取り消された。
When it leaked out that I have a disability, the job offer I had was cancelled.