To Establish
To Set Up, To Configure
する verb
When you establish and determine something, you are making an establishment. When you make that into a verb, you have the word to establish. It also works for tech things, like to set up your computer settings.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well. Careful because the 設 gets shortened to せっ.
あなたの新しいビジネス用のメールアカウントを、グーグルに設定しました。
I set up a new business mail account in Google for you.
クーラーはいつも何度に設定していますか？
What temperature do you usually set your air conditioner to?
今日中に全てのアカウントの二段階認証を設定しないと、会社を首になるんです。
I have to set up two-factor authentications with all the accounts I have by the end of day or I'll get fired.