Fatigue
Weariness
noun, する verb
You're exhausted from labor. From this, you're showing fatigue and weariness.
ひろう
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.
今納税の手続きをしているんだけど、もう疲労困憊だよ。
I’m doing the taxes and I’m already totally exhausted.