That husband and wife had a long, heated argument on whether discussions are indispensable for a good married relationship.
Everybody looked at Mr. and Mrs. Koichi with disapproval.
Mr. and Mrs. Fugu were such smooth operators that they sold tons of seaweed to their neighbors.
You have a husband and a wife. Combine them together and they're husband and wife, or a married couple. This can also be added to a name to mean Mr. and Mrs..
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.