District Of A Town
City Block, Town District, District
suffix
A street you can see with your eye isn't soooo big you can't see it (like a town would be), but it's still pretty big because it has a street. This section of the town is the district of a town, or a city block (though specifically one of an irregular size).
The readings are the ones you learned with the kanji, so use those and you'll be A-Okay.
三丁目
third district
二丁目
second district
一丁目
block one, district one
一丁目のコンビニはオープンしたばかりです。
The convenience store in 1-chome has just opened.
田中さんのアパートは、三丁目です。
Tanaka-san's apartment is in 3-chome.
四丁目にはバスが来ないので、会社までは歩くしかありません。
You have no choice but to walk to the company as there's no bus coming to 4-chome.