Obstruction
Inhibition
noun, する verb, の adjective
Thwart and damage the advancement of something. That's an obstruction and inhibition.
そがい
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.
カフェインを含む飲み物は、睡眠を阻害します。
Drinks containing caffeine inhibit sleep.