Chaining, Connection
Noun and する verb
れんさ
まずはこの負の連鎖を断ち切る必要があります。
First, you must sever ties with this negative chain.
If you take along a chain with you it's still a chain, it's just moving somewhere new.
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.