Since this word consists of a kanji with hiragana attached, you can bet that it will use the kun'yomi reading. You didn't learn that reading with this kanji, so here's a mnemonic to help you: "Hey, you going to quit?" "Yah (や) man, I'm going to quit."
I followed the doctor's advice and quit my job.
Who said Michael resigned as chief editor?
Since Fugu quit the company, I’m thinking about getting him a swim ring as a farewell gift. If anyone wants to join in on my idea, let me know.