The signpost you have your eye on is your goal, target and objective. Just imagine looking at this signpost in the distance. You know you have to get to it from where you are. That is the goal of your journey.

You've had the on'yomi reading of 目 with 目次 way back in level 6. For this vocab, you're trying to get to your goal, that signpost in the distance. As you're trekking towards it there are people standing to the side mocking you, telling you you'll never make it to your goal. Imagine this happening.