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A sacrifice hit is one you do in baseball, when you hit the ball in the air, and then the person on third tags up and scores. In baseball, this can either be a sacrifice bunt or sacrifice fly.
This is a jukugo word that uses the on'yomi readings of the kanji. You've learned the readings for both of these kanji, so you should be able to read this word already!
I can’t help but worry about the sacrifice fly.