Noun and の adjective
むしょく
彼は完璧な夫ですが、一つだけ問題があるんです。十年間ずっと無職なんです。
He would be the perfect husband, save for one thing - he has been unemployed for ten years.
When the status of your employment is "nothing" then you're probably experiencing unemployment.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.