Bitterness
Misery, Hardship, Distress
noun
If you have grief in your eyes, it means you've gone through a lot of bitterness and misery. You can always see in someone's eyes if they've experienced it too.
You'll see this word most often in 憂き目を見る and 憂き目に合う, which both mean "to experience hardship."
This word uses one of the kun'yomi readings for the kanji. You haven't learned this kun'yomi reading for 憂, so here's a mnemonic to help you remember it:
Why the bitterness in your eyes? You visited a famed uni (う) restaurant, only to find it closed and locked. And as a lover of uni, you know no greater misery than to miss out on some uni.
失恋の憂き目に遭いました。
I met with the misery of a broken heart.