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If you profit from the left, you're probably doing everything on the left. That's your good side. You're probably left handed.
The readings are the kun'yomi vocab readings, so combine the readings of the words 左 and 利く together to get the reading of this one. It makes sense since this word is like two words put together.
私は左利きです。
I am left-handed.
左利きの人向けのハサミはありますか？
Do you have scissors for left-handed people?
あなたは右利きですか？それとも左利きですか？
Are you right-handed? Or are you left-handed?
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