Nest
noun
The kanji and the word are exactly the same. That means they share meanings as well.
巣 refers to all kinds of animal homes — a bird's nest, a spider's web, a mouse's burrow, or even a beehive. Sometimes, it can be used figuratively to describe places where people hole up, whether that be a cozy home for lovers or a shady hideout for gangs…
The reading is the same as the one you learned with the kanji.
鳥が木の上に巣を作っている。
The bird is building a nest in the tree.
クモの巣の中に虫が引っかかっている。
There's an insect caught in the spider's web.
近くにハチの巣があるから、気をつけて歩いてね。
There's a bee's nest nearby, so be careful while walking.
巣の中では、ツバメの雛が五羽、ぴいぴい鳴いていました。
There were five baby swallows chirping in the nest.
そのアパートは、オンボロだけど、確かに二人だけの愛の巣だった。
The apartment was shabby, but it was certainly a love nest just for the two of them.