Isolation
Alone, Friendless
noun, verbal noun
When orphans stand, they stand in isolation — alone and friendless. Orphans don't have any parents, so this world can be a pretty cruel place for them. It's really sad.
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.
ある事件があって、職場で孤立してしまったんです。
A certain incident occurred, and I found myself alone and friendless at work.