It'll be hard to make up for the big losses Fugu made by the end of the year.
When I face a hard task, I get excited.
My grandmother has difficulty walking, so I have to help her go shopping today.
You're distressed and it's difficult. This is quite the hardship you're feeling.
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.