To Run A Business
To Manage A Business
The word 営業 is business. The verb version of that (to do a business) becomes to run a business.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well. Also, it shares the reading with 営業.
Our cafe is opening for business as of today.
This shop should have still been in business last month…
Do you know how much money a fortune teller doing business on the street makes?