Commerce
Noun and する verb
しょうばい
一しょに商売して一もうけしようぜ！
Let's go into business and make a fortune together!
最近はあのコンビニのせいで、商売あがったりだね。
My business has dried up recently because of that convenience store.
学校卒業後に商売を始めたんですが、すぐに商売をすることは簡単ではないことを学びました。
After leaving school I went into business for myself, but I soon learned that running a business is no easy task.
A place that sells merchandise is a business.
This is a jukugo word, which usually means on'yomi readings from the kanji. You've learned them both already!