Thank you for your assistance at this time.
Koichi made a phone call to Quentin Tarantino seeking help to increase his YouTube view counts.
You don’t need to request Spider-Man’s assistance.
When you have the power to help someone, you are giving them assistance and support.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.