Including this time, how many times have you come to Japan?
This video is so funny that I have to watch it a bunch of times.
How many times do we have to have this conversation until it finally sinks in? I am not Luke Skywalker. I played him in a movie. My name is Mark. I live in Chicago.
What times? This doesn't make any sense. One thing you'll notice with Japanese and kanji is that 何, when added to other things, often means "how many _____" rather than "what ____." Just something you have to know and experience a bit to catch on to, but you will, I believe in you. So, for this one it's how many times.
This is a jukugo word with a slightly unique reading, where the first kanji uses the kun'yomi reading and the second uses the on'yomi reading. You've seen these readings before, so you should be able to read this alright.