Hangover
noun, verbal noun
On the second day, you experience your drunkenness a different way... in the form of a hangover.
The reading is 二日 and 酔い put together (the reading for that comes from 酔う).
二日酔いだし、足もつるし今日は最悪だよ。
I’m hungover and I also have a cramp in my leg. Today is the worst.