Filthy
Dirty, Unsanitary
noun, な adjective
Not clean things are filthy and dirty. Ewughh.
不潔 is a relatively formal word that refers to unsanitary conditions in personal hygiene, public health, or medical settings. It can refer to both dirty environments and poor hygiene practices. In literature, 不潔 can also describe something as morally dirty to evoke disgust, though this use is somewhat old-fashioned.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.
不潔な手で私をさわらないでください！
Don't touch me with your dirty hands!
不潔な部屋を見て、別れを決意した。
I decided to break up with him when I saw his filthy room.
医者が着る白衣ほど不潔なものはありません。
There is nothing more filthy than a white coat worn by a doctor.